Tetrapyrroles and derivatives
Abcam Dihydrokainic acid, EAAT2 (GLT-1) inhibitor, 1MG
MW 215.25 Da. Selective, non-transportable inhibitor of glutamate transporter EAAT2 (GLT-1) (Ki = 23 μM). 130-fold selective over EAAT1 and EAAT3 (Ki > 3 mM).
The product is subject to the following: Abcam Restricted Use Statement
Abcam SB 242084 hydrochloride, 5-HT2C antagonist, 50MG
MW 431.3 Da, Purity >98%. Potent, selective 5-HT2C antagonist (pKi values are 9 (5-HT2C), 7 (5-HT2B), 6.8 (5-HT2A), 6.4 (5-HT1A), 6.4 (5-HT1B), 6.4 (5-HT1D), 6 (5-HT1E), <6.1 (5-HT1F), <5.5 (5-HT4), 6 (5-HT6), 6.1 (5-HT7), 6.2 (D2), 6.2 (D3) and <5 (α1)). Blood-brain barrier permeable. Anxiolytic activity *in vivo*.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical MethylcobalamIn 500mg
An analog of vitamin B12 with diverse neurological activities; promotes neurite outgrowth and survival in primary CGN and DRG cells and activation of ERK1/2 and Akt from 0.1-100 µM; improves sensory function in a pinch test and increases toe spreading in a rat model of sciatic nerve injury at 1 mg/kg per day; decreases the number of atypical mitochondria in the sciatic nerve and reduces vincristine-induced mechanical allodynia and thermal hyperalgesia in a rat model of neuropathic pain; reduces muscle weakness and forelimb contracture and increases bicep muscle weight and the number of musculocutaneous nerves in the wobbler mouse model of ALS; enhances the recovery of compound muscle action potentials and motor end plate innervation and decreases the time to sticker removal in the sticker removal grooming test in a rat model of bicep ulnar to musculocutaneous nerve transfer
Abcam Endothelin-1 (human, porcine), Vasoconstrictor peptide, 500UG
MW 2491.9 Da. Endothelin-1 (human, porcine), Vasoconstrictor peptide. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
eMolecules 5-Dodecyldihydro-2(3H)-Furanone | 730-46-1 | | 500mg
Toronto Research Chemicals | 5-Dodecyldihydro-2(3H)-Furanone | 500mg | 601595135 | D525920 | | 730-46-1 | | 254.414 | C16H30O2
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Abcam CL-316243 disodium salt, adrenergic-beta3 receptor agonist, 5MG
MW 465.8 Da, Purity >99%. Selective adrenergic-β3 receptor agonist. Induces adipose tissue remodelling in rat. Hypoglycemic agent. Active *in vivo* and *in vitro*.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Cytochalasin D, actin polymerization inhibitor, 1MG
MW 507.6 Da, Purity >98%. Cytochalasin D, actin polymerization inhibitor. Achieve your results faster with highly validated, pure and trusted compounds.
The product is subject to the following: Abcam Restricted Use Statement
Frontier Specialty Chemicals 5G PHTHALOCYANINE
This item has a minimum qty of 2 per supplier requirements.
Phthalocyanine; CAS No: 574-93-6
Apexbio Technology LLC Tin protoporphyrin IX dichloride(Synonyms: Tin Protoporphyrin Dichloride, SnPP, SnPP IX, Tin(IV) Protoporphyrin Dichloride), 25mg, CAS: 14325-05-4.
Tin protoporphyrin IX dichloride (CAS 14325-05-4) is a synthetic metalloporphyrin analog that selectively inhibits heme oxygenase-2 (HO-2) an enzyme abundant in neuronal and endothelial tissues responsible for catalyzing heme breakdown into biliverdin and carbon monoxide (CO) It shows selectivity for HO over endothelial nitric oxide synthase and soluble guanylyl cyclase with IC50 values of 35 and 30 nM respectively In rat neonates administration of this compound suppresses the physiological increase in HO activity post-birth and prevents neonatal hyperbilirubinemia demonstrating utility in biomedical research on heme metabolism pathways
Selleck Chemical LLC Protoporphyrin IX (PPIX) S5145-1g
Protoporphyrin IX (PPIX) is a heterocyclic organic compound which consists of four pyrrole rings and is the final intermediate in the heme biosynthetic pathway
Medchemexpress LLC Biliverdin hydrochloride | 856699-18-8 | MFCD06245593 | 99.3% | 619.11 g/mol | C33H35ClN4O6 | 5 MG
Biliverdin hydrochloride is a water-soluble tetrapyrrolic bile pigment produced during heme catabolism. Supplied as a green to dark-green solid, it is used as a biochemical reagent in studies of heme metabolism, oxidative stress, and inflammation. Analytical identifiers include CAS 856699-18-8, formula C33H35ClN4O6, and molecular weight 619.11 g/mol.
- High purity (99.3%) suitable for in vitro biochemical applications.
- Available in small research pack sizes, including 5 mg, for assay development.
- Soluble in DMSO (20 mg/mL) with warming or sonication; low water solubility.
- Store sealed, away from moisture; stable at -20°C, with longer stability at -80°C in solution.
- Green to dark green solid allowing easy visual confirmation of material.
Frontier Specialty Chemicals 100MG COPROPORPHYRIN III TETRA
Coproporphyrin III tetramethyl ester; CAS: 5522-63-4; 100mg